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Interestingly, restoration of SIRT1 expression both suppressed ferroptosis and increased GPX4 levels, despite the absence of a significant difference in GPX4 expression between SYNCRIP KO and control cells (Figure 3D)

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Simulating the TREK-1 receptor may reduce neuron excitability, whereas reducing the receptor activity may increase neuron excitability

10.1007/s10620-008-0598-y 107 SiegallC