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In REDEFINE 1, adults with obesity or overweight (without diabetes) treated with CagriSema had a mean body weight reduction of 20.4% at 68 weeks under the treatment-policy estimand, compared with 3.0% on placebo

The other 80 percent passes into the small intestine, where absorption is faster

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Current studies mainly focus on combinations with dietary control, exercise, and other weightloss agents, aiming to enhance efficacy and reduce side effects

Ohnishi et al., 2008)

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