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Nausea is the most common, with relative risk ratios of 2.69 at 4 mg, 4.27 at 8 mg, and 4.00 at 12 mg compared to placebo
(Tirzepatide is the active ingredient in Eli Lilly's obesity drug Zepbound.) She'd been taking the drugs already, from a local provider, and called them "life-changing," but made the switch to Zappy hoping to save money
It is important to note that all current evidence derives from in vitro cellular models and in vivo animal studies, and no human clinical trials have been conducted as of February 2026
Burgos RA
doi: 10.1007/s12011-018-1558-9
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