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Starting or stopping hormonal forms of birth control or undergoing hormone replacement therapy can also trigger melasma

p53 can be rapidly activated to induce cell cycle arrest when retinal cells are subjected to photodamage, hypoxia, or metabolic stress, enabling DNA repair (83)

reported that in the liver of HFD-fed mice, lipid peroxides were elevated while the level of total glutathione remained unchanged [22]

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