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[DOI] [PubMed] [Google Scholar] 92.Spee B., Arends B., van den Ingh T.S.G.A.M., Penning L.C., Rothuizen J

An 8-week double-blind randomized placebo-controlled trial in 62 patients with PWS demonstrated an improvement of hyperphagiaevaluated as behavior and severity scores by Dykens Hyperphagia Questionnaireafter Topiramate group versus placebo group, with no effects on BMI [95]

These findings highlight the complexity of necroptosis in AP pathogenesis and underscore the need for further mechanistic studies

In conclusion, neuroimmune interactions within the gut-brain axis have emerged as a promising area of epilepsy research

Because danuglipron and orforglipron also did not alter anxiety-like behaviour in the open field test or elevated plus maze (Extended Data Fig

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