GLP ones may have benefits for cardiovascular disease, for, uh, metabolic disease
Sugianto JZ, Ralston JS, Metcalf JS, McFaddin CL, Smith MT
Unlike synthetic B12 forms, methylcobalamin is ready for the body to use immediately and does not require conversion
The American Diabetes Association recommends reassessing glycemic control within 3 months of any significant medication change
IM B12 injection is especially appropriate when oral supplementation has been inadequate, when absorption is compromised, or when neurological symptoms are present (Stabler, New England Journal of Medicine , 2013)
Because most evidence is still preclinical or anecdotal, symptom tracking is more useful than expecting a fixed timeline