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1 Of particular interest in this article is the function of GLP-1 as a hormone released by the gut during periods of eating that then stimulates the secretion of insulin
A 2025 study directly challenged this in -cells, finding that cAMP/PKA/ERK signaling is diffusely distributed across the cell regardless of internalization kinetics, and that fast-internalizing agonists are paradoxically less efficient drivers of insulin secretion from perfused rat pancreata (Chen et al., 2025)
Then, this toxic compound accumulates in the liver and causes damage
High-fiber foods slow gastric emptying and promote satiety, complementing GLP-1's effects
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