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The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]

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This is an added safety measure to protect the very top layer of the skin, which is the area most prone to damage with laser treatments, especially in patients with darker skin