Martelli and Giacomini 2018)
Even if virtually, all cell types synthesize GSH, the main source of the tripeptide is liver where the bulk of cysteine, the rate limiting amino acid, derived from diet is metabolized
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Taking into account that the redox processes are not spontaneous in cells, but the adequate reaction velocity and appropriate specificity are achieved by the catalyzing activity of enzymes, special attention has raised toward the glutathione-utilizing enzymes
