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Dr Hviid said: Because of the high cost, we assume that compliance is very high among the women prescribed GLP-1 RAs. In an invited commentary accompanying the paper, Drs Yeyi Zhu and Monique Hedderson, from Kaiser Permanente Northern California and the Center for Upstream Prevention of Adiposity and Diabetes Mellitus, in Pleasanton, California, USA, write that the studys findings complement and extend an emerging evidence base on the reproductive safety of GLP-1 RAs. They continue: For clinicians, the study by Hviid et al (2026) may inform preconception and early pregnancy counseling