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10.1016/j.metabol.2016.03.009 Metabolism 25 FontanellaR.GhoshP.PesapaneA.TaktazF.PuocciA.FranzeseM.et al (2024)

Among subjects receiving VK2735, all treatment emergent adverse events (TEAEs) reported to date have been mild or moderate, with the majority (76%) reported as mild

The 12 mg group lost an average of 24.2% body weight at 48 weeks versus 22.8% in the 8 mg group, a difference of 1.4 percentage points

Furthermore, the amount of the medication that might remain in the plasma after the separation process is negligible

Hypoglycemia risk increases when used with insulin or sulfonylureas

The benzyl alcohol acts as a preservative, allowing multiple sterile withdrawals from the same vial