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Large tumors can compress surrounding structures, primarily the normal pituitary gland and optic (visual) pathways, causing symptoms

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Kwee SA, Hedrick TL, Abell TL

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Visualization of melatonins multiple mitochondrial levels of protection against mitochondrial Ca(2+)-mediated permeability transition and beyond in rat brain astrocytes

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Tresiba has no effect on appetite or eating behavior

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