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In the presence of publication bias, trim and fill analysis was used to simulate a model without publication bias presenting a new effect size by inserting new fictitious studies

BPC-157 , a synthetic peptide originally studied in gastrointestinal healing research, activates the VEGF receptor 2 (VEGFR2) directly and promotes new blood vessel formation

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PMID: 28450121

It pairs that with pancreatitis, which it calls rare but serious, noting that sudden severe abdominal pain warrants immediate evaluation

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