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Pernicious anemia D51.0 applies when the provider documents pernicious anemia (B12 deficiency anemia due to intrinsic factor deficiency, often associated with autoimmune gastritis)

Active ingredient: minimum 1.0%

And when the immune system is repeatedly exposed to these triggers, the dysregulation that follows can manifest as, or accelerate, autoimmune disease (20)

This translates to approximately 1.6 to 4 mcg per kilogram of body weight, extrapolated from effective rat doses using standard interspecies scaling factors

a maximum of approximately 10% inhibition of COMT at 600 M (no curve could be fitted)