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Neuroendocrine Links to Sleep Patterns Growth hormone release is tightly linked with circadian rhythm and sleep regulation

The study's single-blind design and placebo control add credibility, but the very small sample size means the results should be interpreted cautiously

We found that cancer cells with -KG insufficiency exhibit cytosolic NADPH depletion because of defective FAO and TCA cycle, highlighting the importance of -KG in regulating NADPH homeostasis through mitochondrial metabolism

In a primary study using germ-free mice, Braniste et al