The key role of Ca 2+ is ATP synthesis and mitochondrial ROS formation through oxidative phosphorylation and activation of enzymes (Lewis et al
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Koike K, Ishigami A, Sato Y, et al
Journal of Crohn's & Colitis, 7 (9), e358e366
(1996) A multicenter study of sleep-wake rhythm disorders: therapeutic effects of vitamin B12, bright light therapy, chronotherapy and hypnotics