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MMWR Surveill Summ 2009

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BE AWARE WITH SHOTS: Doctors typically give shots using cyanocobalamin, and many may not respond well to that form of B12 (especially when given at a high dose), you may have negative side effects

This finding highlights the value of untargeted metabolomics in capturing the expected biochemical signature of MMA and suggests that broader metabolite profiling may provide complementary information alongside conventional biochemical testing and confirmatory diagnostic approaches

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There are potential limitations of their use in clinical studies