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Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, et al

Losing weight more gradually and deliberately will yield a better outcome than simply focusing on how quickly the scale can drop

When available, the results of these two clinical studies may enhance our understanding of the mechanisms of stroke protection by GLP-1RAs in humans

The primary evidence comes from the 2017 Cell paper using aged and chemotherapy-treated mice, and subsequent mechanistic studies

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