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Due to its good spatial and temporal resolution and relative ease of recording, it is widely used as a biomarker of disease and as a tool to measure the brains activity to monitor the effectiveness of disease treatment [26]

SIRT1 deacetylates NF-B, suppressing its transcriptional activity, which ultimately reduces macrophage infiltration and the release of pro-inflammatory cytokines [38]

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Comprehending the molecular mechanisms that drive EMT in DKD is vital to formulate precise therapeutic approaches against tubular injury