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Free radicals are molecules that are potentially toxic to cells
In a neonate requiring urgent dialysis, the need for a small catheter size and the small volume of the dialysate circuit can limit ammonia clearance
That vote did not approve MOTS-c for weight loss, metabolic disease, longevity, exercise performance, or osteoporosis
Major Criteria Congenital multiple contractures, characteristically adduction-flexion contractures and/or talipes equinovarus (clubfoot) Characteristic craniofacial features, which are evident at birth or in early infancy Characteristic cutaneous features including skin hyperextensibility, easy bruisability, skin fragility with atrophic scars, increased palmar wrinkling Minor Criteria Recurrent/chronic dislocations Pectus deformities (flat, excavated) Spinal deformities (scoliosis, kyphoscoliosis) Peculiar fingers (tapering, slender, cylindrical) Progressive talipes deformities (valgus, planus, cavum) Large subcutaneous hematomas Chronic constipation Colonic diverticula Pneumothorax/ pneumohemothorax Nephrolithiasis/cystolithiasis Hydronephrosis Cryptorchidism in males Strabismus Refractive errors (myopia, astigmatism) Glaucoma/elevated intraocular pressure Myopathic EDS (mEDS) If a person meets the diagnostic criteria for mEDS, genetic testing should be done to confirm the diagnosis
Model data can support research hypotheses
