"Based on our study, we recommend that guidelines be updated with the following precautions for GLP-1 RA users undergoing endoscopic procedures: continue therapy, follow a liquid-only diet the day prior, and adhere to standard pre-anaesthesia fasting," said lead author, Dr Brent Hiramoto, senior gastroenterology Fellow at Brigham and Women's Hospital
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Also, studies carried out in cancer-associated fibroblasts derived from breast cancer patients show that the GPER-1/EGFR signaling axis increases the expression of several cell cycle regulatory genes (Pisano et al., 2017)
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Clinical trials of GLP-1 medications have consistently demonstrated that whilst participants lose considerable weight, a proportion of this weight loss includes lean body mass
