doi:10.1016/j.eclinm.2024.102475 6
(IK) Expression levels of SREBP-2 and HMGCR were analyzed using Western blotting, and -actin was used as the loading control
This rebound can be frustrating and may lead to a cycle of weight loss and regain, making it difficult for some people to maintain their progress
For differential expression testing, the R package DESeq2 (v.1.30.1) was used to identify differentially expressed genes
These treatment conditions were chosen to mimic excess heme from chronic hemolysis and systemic hypoxic conditions that occur in SCD patients 1,2,11
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