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It arises due to a combination of genetic and lifestyle factors that contribute to defective production of insulin from pancreatic beta cells, and/or resistance to its uptake by insulin receptors located in peripheral and central tissues in the body

While there is some truth to this, the reality is more complex

We did not have the opportunity to study contractility in human ventricular tissue for lack of access

Those with prior pancreatitis, severe gastrointestinal disease, pre-existing diabetic retinopathy, or significant cardiovascular conditions also require careful riskbenefit assessment before use

It is a tool, one piece of a much bigger lifestyle shift

It interacts with barrier function, immune activity, oil production, moisture balance, and the local environment