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VIP, a 28-amino acid peptide, exhibits a diverse range of biological activities due to its interactions with multiple G protein-coupled receptors (GPCRs) from the VIP/PACAP receptor family (Harmar et al., 2012)

N Engl J Med 384(18):17191730 Tinsley GM, Heymsfield SB (2024) Fundamental body composition principles provide context for Fat-Free and skeletal muscle loss with GLP-1 RA treatments

doi: 10.1016/j.celrep.2023.113326

And so it just drives up demand for cellular fuel

Accordingly , these activities do not include clinical, cosmetic, therapeutic, or diagnostic use

This relates to the inflammatory response triggered by the treatment