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Target minimum fluid intake of 64-80 ounces daily, with additional water consumed around training sessions

It also slows gastric emptying, meaning food stays in your stomach longer, which contributes to the feeling of fullness

Side effects looked very similar to other GLP-1 medications, especially during dose increases: Nausea Diarrhoea Constipation Vomiting These were more common at higher doses

This occurs as the receptors work together to deliver satiation signals to the brain

In the Phase 3 TRIUMPH-1 trial, the highest-dose retatrutide group averaged 28.3% weight loss at 80 weeks

Then, the doctor increases the dose to 0.5 mg once weekly for another four weeks