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They were randomly assigned to receive different doses of Retatrutide or a placebo over 48 weeks

In clinical care, eligibility determines whether a patient is an appropriate candidate for treatment

Jason Brett, principal US medical head for Novo Nordisk, told CNN in an interview

The visible results of inflammation reduction include reduced facial puffiness, improved skin quality (clearer, more even tone, reduced redness), decreased joint swelling and pain, improved eye appearance (reduced under-eye bags and redness), and a general appearance of vitality that people describe as looking younger and healthier

Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas