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Androgen receptor expression is a predictor of poor outcome in urothelial carcinoma

Early supplementation can help maintain optimal levels and prevent the deficiency from progressing

Key limitations include poor bioavailability, rapid metabolism, and restricted penetration across the bloodnerve barrier

J Clin Endocrinol Metab (2008) 93:120310.10.1210/jc.2007-1986 28 TaboadaGFLuqueRMNetoLVMachado EdeOSbaffiBCDominguesRCet alQuantitative analysis of somatostatin receptor subtypes (1-5) gene expression levels in somatotropinomas and correlation to in vivo hormonal and tumor volume responses to treatment with octreotide LAR