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That involves comparing the performance of a drug with that of a placebo

The most common side effects with the 12 mg dose were nausea (43.2%), diarrhea (33.1%), constipation (25.0%), and vomiting (20.9%)

-barr1-KO mice and their control littermates did not show any statistically significant differences in body weight or fed and fasting blood glucose and plasma insulin levels (Supplemental Figure 2)

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