Numerous studies have highlighted the impact of oxidative stress on MSC differentiation into osteocytes [40] and chondrocytes [41] via the regulation of differentiation signaling cascades [42, 43]
Study by Handog et al
doi: 10.1111/imr.13429 58 LeiSLiuKLiuCAnRBaoZZhangHet al
PMID 39049203 Martinelli S et al
Lilly announces $3bn expansion to injectable drug manufacturing facility The pharma giant is expanding its site in Pleasant Prairie, Wisconsin after acquiring the facility from Nexus in April
While gastrointestinal AEs such as nausea and vomiting dominate safety reports 8 and recent pharmacovigilance studies highlight increasingly recognized risks including acute pancreatitis, nephritis, hypotension, and syncope 9,10,11 , emerging data suggest that GLP-1 RAs may be associated with neurological adverse events (NAEs) 12,13