Ultrasound-responsive liposomes for targeted drug delivery combined with focused ultrasound
One compound tried to bypass appetite regulation entirely and got outcompeted by biology
LCMS/MS analysis was performed using an Advance nanoLC (BrukerMichrom, Auburn, CA, USA) and LTQ linear ion trap mass spectrometer (Thermo Fisher Scientific) equipped with a NANOHPLC capillary column C18 (0.075 mm ID 150 mm length, 3 m particle size, Nikkyo Technos, Tokyo, Japan) using a linear gradient (25 min, 535% CH 3 CN /0.1% formic acid) at a flow rate of 300 nL/min
doi: 10.1080/00365521.2016.1192678
In light of this, the Aalto-Helsinki iGEM team decided to explore a better treatment alternative to improve accessibility, enhance patient experience, and partly relieve the strain on both the healthcare system and the environment caused by the current standard of care
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