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Of these contact pairs, intrahelical contacts were more common in ligand-specific structures compared to other groups which harbored more interhelical contacts (Fig

Both peptides are synthetic in origin, produced by solid-phase peptide synthesis and purified to not less than 98% by reversed-phase HPLC, with identity confirmed by mass spectrometry

Glutathione exists primarily in two forms: Cells continually recycle oxidized glutathione back into its reduced form

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Also, additional LDHB silencing in KRAS -mutated A549 cells further reduced cell viability after combined treatment with 4CBA and RSL3 (Supplementary Fig