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So, it is always better to consult your physician rather than self-administering yourself to prevent any side effects of the medication

It has also been suggested that delayed emptying of the lower GI tract in one-half of GERD patients leads to an increase in intragastric pressure, and that a decrease in barrier pressure (the difference between the lower sphincter pressure and the intragastric pressure) is one of the factors contributing to the pathogenesis of GERD (71)

Braz.J Med.Biol.Res

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Khadir F, Pouramir M, Joorsaraee SG, Feizi F, Sorkhi H, Yousefi F

Pharmacological blockade of group II metabotropic glutamate receptors reduces the growth of glioma cells in vivo