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Clinical studies A total of 22 completed clinical studies were identified (Table 1 and Extended Data Tables 1 and 2), with another 8 clinical trials still ongoing (Supplementary Section 3)

But their side effects do not seem significantly different from injectable versions of semaglutide and tirzepatide (Zepbound)

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Treatments like fractional resurfacing lasers, radiofrequency microneedling, and other collagen-induction therapies work by creating controlled micro-injury in the skin - wound healing is one of the strongest triggers for new collagen formation

Patients taking insulin or sulfonylureas alongside retatrutide face an increased risk of hypoglycaemia and require close monitoring

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