Its availability exists in a highly restricted regulatory gray zone
Microdosing refers to administering chemicals at levels below therapeutic doses
Medication, Prescription Drug, and Topical Product Interactions Topical GHK-Cu may interact practically with other skin products by increasing irritation risk, especially in people using retinoids, acids, exfoliants, medicated creams, or post-procedure regimens
Biotinylated GHK incorporated into collagen matrices has been evaluated in rat dermal wound models, demonstrating enhanced healing compared to plain collagen controls
The rationale is that under normal physiological circumstances, the decline in IGFBP-1 from its maximally stimulated overnight fasting level (34) to the level seen after food intake on a molar basis is relatively modest, and only leads to minor increases in serum free IGF-I (37, 38)
Sci Rep (2022) 12:10484