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Furthermore, incretin-based therapies (GLP-1 receptor agonists and dual agonists such as tirzepatide) improve hepatic steatosis, modulate inflammatory responses, and protect -cell function, illustrating how mechanistic insights can be translated into pharmacological strategies (203205)

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Insulin Sensitization: Its primary metabolic benefit is increasing skeletal muscle insulin sensitivity and promoting GLUT4 translocation, which drives glucose clearance from the blood

doi: 10.2337/dc19-0883 29 RosenstockJAllisonDBirkenfeldALBlicherTMDeenadayalanSJacobsenJBet al