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But if you accidentally inject two doses one day apart, or forget which day you are on and double up, the resulting concentration spike can cause significant side effects including severe nausea, gastrointestinal distress , and potentially hypoglycemia in those also taking diabetes medications

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The timing question matters because inflammatory cytokines follow diurnal patterns - IL-6 and TNF- typically peak in early morning (6-8 AM), suggesting morning dosing might intercept inflammation at its highest point

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