That includes one of the most important: the immune system
Requirements of vitamin B12 in excess of normal (due to pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy, hepatic and renal disease) can usually be met with oral supplementation
Precautions General Precautions: Vitamin B 12 deficiency that is allowed to progress for longer than 3 months may produce permanent degenerative lesions of the spinal cord
Certain medical conditions should also be noted, such as kidney disease, low potassium and other nutritional deficiencies
separation occurs in the terminal ileum in the presence of calcium, and vitamin B 12 enters the mucosal cell for absorption
Laboratory Tests During the initial treatment of patients with pernicious anemia, serum potassium must be observed closely the first 48 hours and potassium replaced if necessary