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4 integrates extracellular stress and growth cues to regulate cell-cycle progression, apoptosis, and differentiation, and frequently cooperates with NF-B signaling to promote cancer cell survival and metastasis

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Gastrointestinal adverse effects are among the most common side effects of GLP-1 agonists, including nausea, vomiting, diarrhoea, and reduced appetite

The FDA and major drug interaction databases do not flag this combination as contraindicated or requiring dose adjustment

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