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This distinction matters: Quite a few menopause symptoms are caused by low estradiol levels, and many hormonal treatments for menopause symptoms specifically use estradiol

BPC 157 and Blood Vessels. Current Pharmaceutical Design (2014)

We treat it like medicine, which means saying no when the patient isnt ready, monitoring closely when they are, and adjusting protocols based on what bloodwork shows rather than what the patient wants to hear

TT are rare in childhood (12%) [276], but increase to 15% during adolescence [274]

[6] Huang, T., et al