Accumulated oxidized lipids are metabolized by 12/15-lipoxygenase, and metabolite products activate AIF to promote apoptotic cell death [16]
Zhang L, Wu P, Zhang L, SreeHarsha N, Mishra A, Su X
Parkinsons corrupts the parts of the brain that make dopamine, a chemical instrumental in coordinating the bodys movements
[DOI] [PMC free article] [PubMed] [Google Scholar] 25.Board P.G., Coggan M., Chelvanayagam G., et al
Conjugation It binds to toxins, forming conjugates that are more easily eliminated from the body, aiding in detoxification
If considering Lurcher mice as a model of a particular disease (nosological unit, disease sui generis ), identical etiology and primary mechanisms of its action on the organism are also of importance