Roches Genentech announced last week that its candidate CT-388, which was part of the $2.7 billion Carmot buy, lowered body weight by 18.8% in a Phase I trial
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Specifically, the inclusion of the SURPASS-CVOT trial, which compares tirzepatide against dulaglutide rather than semaglutide, is explicitly justified as it provides vital contextual cardiovascular outcome data for tirzepatide in the absence of a completed head-to-head cardiovascular trial between the two primary agents
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10.1002/prp2.645PubMed Abstract | CrossRef Full Text | Google Scholar 82 LiM.de GraafI
