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The medullary tissue is composed of unique postganglionic SNS neurons called chromaffin cells, which are large and irregularly shaped, and produce the neurotransmitters epinephrine (also called adrenaline) and norepinephrine (or noradrenaline)

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RANKL is a type II transmembrane protein of the tumor necrosis factor (TNF) superfamily with an N-terminal region and a C-terminal receptor binding domain (Nelson et al., 2013)

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