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Lancet (2002) 360(9328):21923

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A.Hernndez-CruzA.CorkidiG.ViscontiP

We propose that chronic exposure to a particular suite of environmental and genetic factors elicits a trajectory of impaired mitochondrial biology that maximally impacts subsets of mitotypes abundant in the hippocampus, entorhinal cortex, and cerebral cortex, which eventually surfaces as the hallmark features of AD

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In the condition of increased dopamine release and synthesis induced by amphetamine, NaBPC157 could both prevent and reverse the consequent disturbances (i.e., stereotyped behavior)