Dec 28 2005;294(24):3101-3107
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Strategies such as surface modification, hydrogel encapsulation, or scaffold-assisted delivery may improve targeting and therapeutic persistence in the joint cavity (186)
Other GLP-1s have not listed dysesthesia as an adverse effect
Clinical assessments were conducted every 3 months to evaluate efficacy, measured as percentage of total weight loss (%TWL), excess weight loss (%EWL), changes in BMI, and improvement in comorbidities, as well as tolerance, monitored for adverse effects including gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea) and discontinuation rates
The necessity for multiple doses each day could decrease patient compliance and satisfaction regarding their treatment plan