J Ethnopharmacol (2008) 118:4359
Researchers have shown that, by stabilizing blood sugar, improving insulin sensitivity, and reducing glucose spikes, GLP-1s may help lower the metabolic burden placed on tissues over time, which is a key factor in preserving long-term healthspan
Day 61 and onward: Increase to 14mg once daily if further glycemic control is needed
That said, research on GLP-1 related gastrointestinal side effects generally points to hydration and fiber as the first steps most providers recommend, since they address the root cause of slower gut motility without adding another medication into the mix
Benefits: Increases metabolism
Alternative medication classes for diabetes (such as SGLT2 inhibitors) or weight management should be considered, recognizing that heart rate increases can occur with other GLP-1 receptor agonists as well