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Bronden, A

integrated the tumor-penetrating and -targeting cyclic iRGD peptide with a PROTAC to form IPR (Fig

Originally approved for the treatment of type 2 diabetes, semaglutide works by mimicking the action of GLP-1, a hormone involved in blood sugar regulation and appetite control

Focusing on the GLP-1 receptor, semaglutide mimics the gut-produced hormone GLP-1, which signals fullness to the brain, whilst also stimulating insulin secretion, reducing glucagon secretion, and delaying gastric emptying

Kothare PA, Linnebjerg H, Skrivanek Z, et al

Contrairement l'amylasmie qui peut augmenter dans un nombre important de situations, la lipasmie n'est majore que lorsqu'il existe une pancratite aigu