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Diabetes Care 2023;46:384390

According to leading biochemical research resources, its role in maintaining highly efficient mitochondrial function allows specialized investigators to study how cells respond to sudden increased energy demands

Absence of this effect may indicate the need for dose adjustment, additional investigations, or consideration of alternative or adjunctive therapies

These diseases include chronic obstructive pulmonary disease (COPD), bronchial asthma, acute lung injury (ALI), chronic granulomatous disease (CGD), nonalcoholic fatty liver disease (NAFLD), hepatic ischemiareperfusion (IR) injury, kidney fibrosis, acute kidney injury (AKI), cardiovascular disorders, and cancer (Figure 2

J Clin Endocrinol Metab 2011;96:13011310