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Previous [ 68 Ga]Ga-DO3A-Tuna-2 dose finding experiments in non-human primates by PET/CT demonstrated that injected doses of in excess of 0.20 g/kg DO3A-Tuna-2 tended to begin to saturate the GCGR in the liver 8

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In many cases, the cause is unknown (ie, the infertility is said to be idiopathic)

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This narrative review discusses naturally occurring compounds that have been researched in animal models, in vitro cell lines, and clinical trials to inhibit pathological IgE