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In mitophagy, PINK1/parkin-dependent phosphorylated Miro is targeted to proteasome degradation, thus quarantining damaged mitochondria from further transport (Wang et al., 2011)

Antagonism of ADORA2A by KW6002 attenuated mitochondrial levels and co-localization of EPAC1 and VDAC1

10.3389/fmed.2022.878601 196 YuP.ZhanM

Importance of regional adipose tissue distribution

These neuroprotective properties position Pinealon as a valuable research tool for advancing our understanding of neurological aging, developing strategies for cognitive preservation, and investigating the fundamental mechanisms that maintain brain health throughout the lifespan

& Tamura, T