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Advancing neuroprotection requires greater conceptual clarity, inclusivity, and technological innovation to overcome current barriers

KPV enters cells via a transporter that is upregulated in inflamed tissues, providing targeted delivery to areas of active inflammation

Rather than being a pharmaceutical development, this tripeptide occurs naturally in human blood plasma, with concentrations around 200 ng/mL at age 20 that decline to approximately 80 ng/mL by age 60

Furthermore, the systemic neuroinflammation driven by this oxidative stress directly impacts the autonomic nervous system

10.1626/pps.13.164 152 YeX

Following washing with PBS, the primary antibody, CD36 (5114-PE100T, 1:20 dilution, BioCytex), was added, and cells were incubated at 4 C overnight